Professor Dongsheng Liu's group located in the Department of Chemistry, Tsinghua University
We are interested in using biomolecules and their specific interaction in nanostructure fabrication and nanodevice design, which include: DNA molecular machines and related nanodevices based on DNA tetrads; 2D and 3D nanostructures self-assembly by DNA/protein/nanoparticle; molecular devices’ application in diagnosis; bio-inspired smart materials; DNA sequence and secondary structure relationship.
The research in our lab has extensive related disciplines including Biology, Chemistry, Physics, Material Sciences and Nanotechnology. Our interests are using biomaterials to fabricate nanostructures and nanodevices with utilities. We have established a pH triggered DNA motor based on a tetraplex DNA structure, studied its mechanism and driven methods and used it to realize meaningful applications. We have also coupled DNA with proteins, linear polymers, dendrimers and nanoparticles to construct functional self-assembly structures.