Liu's Lab

1. First DNA nanomachine running at milliseconds level;
2.Driven by pH changes: clean, fast and reliable;
3.Force output was demonstrated at single molecular level;
4.Nanocompartment, logic gate, smart nanopores, smart surface and other devices based on the nanomachine.

Related Publications:
Acc. Chem. Res., 2014, 47, 1853
Angew. Chem. Int. Ed., 2003, 42, 5734
J. Am. Chem. Soc., 2005, 127，17054
 Angew. Chem. Int. Ed., 2007, 46, 3915
J. Am. Chem. Soc.,2012, 134, 1416

The Frame Guided Assembly (FGA)

1. Inspire by the cell structure (lipid bilayer/membrane protein/skeleton);
2. Using same molecular system and under the same condition, the size and shape of final assemblies could be precisely controlled;
3. A general method that can be applied to any amphiphilic molecular systems.

Related publications：
Angew. Chem. Int. Ed.,2014, 53, 2607
Adv. Mater. 2016, 28, 9819
Angew. Chem. Int. Ed. 2017, 56, 1586

DNA Supramolecular Hydrogels and their applications

1. Fast forming at seconds level;
2. Biocompatible;
3. Designable mechanical properties;
4. Excellent permeability to macromolecules including proteins;
5. Injectable and suitable for 3D living cell printing.

Related Publications:
Acc. Chem. Res., 2017, 50, 659
Advanced Materials, 2011, 23, 1117
Angew. Chem. Int. Ed. 2015, 54, 3957