Functional DNA assembly material



DNA as a programmable polymer has been used to fabricate delicate structures and assemble irregular hydrogel. For our group, we have used a Y shaped DNA structure with half-i-motif ends to construct a pH responsible gel/sol transform system with peerless efficiency.

Another Y shaped motif combined with a dsDNA with complemented stick ends and restriction endonuclease sites brought out a novel DNA gel responded to both temperature and enzyme. Moreover, several well designed Y shape motifs can also assemble into dendrite super molecules step by step.

These gel or dendrite DNA systems have the potential to be used as containers both in macro and in nano scales.



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